Alimentary Health Expertise >> Achievements

The Irritable Bowel Syndrome ("IBS") market is a large and under penetrated market (estimated to affect between 9 and 12% of the Western adult population) and is therefore an attractive one for the development of novel, safe and efficacious therapies. Given its prevalence, analysts predict that IBS could represent a global market on par with the current gastroesophageal reflux disease ("GERD") market estimated at more than $13.5bn in 2003 according to Ashburn et al in Nature Reviews Drug Discovery April 2006 edition and depression estimated at $16bn in 2002 by Datamonitor.

AH has successfully conducted two positive clinical studies in this indication, with a lead candidate product which it believes meets the aforementioned criteria.

The results of the initial clinical trial supporting this product made the cover and has been published in the March 2005 Edition of GASTROENTEROLOGY, a global peer reviewed gastrointestinal medical journal - the most cited publication in Gastroenterology in 2006.

The results of the second study have been presented at Digestive Disease Week (DDW) in Chicago in May, the World Congress of Gastroenterology in Montreal in September, and the American College of Gastroenterology in Honolulu in October 2005, and published in the American Society of Gastroenterology Journal.

Based upon these studies and following a six year research alliance, Procter & Gamble have licensed the global Over the Counter ("OTC") gastrointestinal ("GI") rights to this technology from AH and subsequently launched an OTC dietary supplement product on the U.S market in October 2005.

This product, a scientifically selected proprietary probiotic bacterium, is based on AH’s lead candidate probiotic B. infantis 35624 which has been clinically proven to reduce the severity of the symptoms of IBS and is marketed under the brand name - Align.

Information on Align >>

AH has also established partnerships with Mead Johnson Nutritionals for infant nutrition products and a leading animal nutrition company for companion animal products.